Endocrine Abstracts

Introduction/aim: There is growing evidence to suggest that retinal neurodegeneration is an early event in the pathogenesis of diabetic retinopathy (DR). Somatostatin (SST) has a neuroprotective action and we previously found a downregulation of SST associated with the hallmarks of retinal neurodegeneration (glial activation and apoptosis) in human retinas. The aim of the study was to test the hypothesis that SST is useful in preventing retinal neurodegeneration.<p class="...